Background Global regression models under an implicit assumption of spatial stationarity were commonly applied to estimate the environmental effects on aquatic species distribution.However, the relationships between species distribution and environmental variables may change among spatial locations, especially at large spatial scales with complicat
Summary: B7-H3, an immune checkpoint molecule, is prominently overexpressed in various solid tumors, correlating with poor clinical outcomes.Despite its critical role in promoting tumorigenesis, metastasis, and immune evasion, the regulatory mechanisms governing B7-H3 expression, particularly in cancer stem cells (CSCs), remain elusive.In this comp
Autoregulation of nodulation (AON) is a long-distance signalling regulatory system maintaining the balance of symbiotic nodulation in legume plants.However, the EV Charger intricacy of internal signalling and absence of flux and biochemical data, are a bottleneck for investigation of AON.To address this, a new computational modelling approach calle